xanthoma Definitions


a small, yellow nodule, rich in cholesterol and other lipids, that occurs in the skin, often near a joint

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  • xanthomas are deposits of fat that build up under the skin. they may appear as small yellow bumps or as flat, wide plaques on your elbows, knees, hands, feet, or buttocks. a type of xanthoma called xanthelasma palpebrarum appears on the eyelids. these yellow, fat deposits can potentially be signs of heart disease because they may indicate high levels of fats in the blood. everydayhealth.com

  • the lesions illustrated here are typical of xanthoma striatum palmare, a form of planar xanthoma. this patient also has biliary cirrhosis. note how the yellowish papules and plaques follow the creases of the fingers and the palmar folds. the familial hyperlipidemias, particularly types ii, iii, and v, may present with an identical clinical picture. patients with these disorders are at high risk for ischemic heart disease. medicinenet.com

  • the presence of the small, tender, and skin-colored or red nodule in a patient with compatible symptoms is diagnostic. rarely, an achilles tendon xanthoma develops at the top edge of the posterior shoe counter but tends to be pink and asymptomatic. achilles tendon enthesopathy causes pain mainly at the tendon’s insertion but may also cause pain at the top edge of the posterior shoe counter. enthesopathy is differentiated by the absence of a soft-tissue lesion. merckmanuals.com