xanthomatosis Definitions


a disorder in which excess lipid accumulates in the body and produces xanthomas

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  • out-of-control diabetes can cause eruptive xanthomatosis — firm, yellow, pea-like skin growths. the bumps have a red halo around them and may itch. they’re usually found on the backs of hands, feet, arms, and buttocks. this skin problem usually strikes young men with high cholesterol and very high triglycerides (fat in the blood). getting blood glucose levels down is the main treatment for these skin sores. your doctor may prescribe drugs to lower cholesterol and triglycerides. everydayhealth.com

  • xanthomatosis: a condition in which fatty deposits occur in various parts of the body. these fatty deposits are called xanthomas or xanthomata and appear as yellowish firm nodules in the skin. xanthomas are in themselves a harmless growth of tissue. however, they frequently indicate the presence of underlying diseases such as diabetes and disorders of fats (lipid disorder or hyperlipidemia). medicinenet.com

  • other features of cerebrotendinous xanthomatosis include clouding of the lenses of the eyes (cataracts) and chronic diarrhea in childhood; a reduced ability to produce and release a digestive fluid called bile (cholestasis), which can lead to a yellowing of the skin or whites of the eyes (jaundice); and progressively brittle bones that are prone to fracture (osteoporosis). people with cerebrotendinous xanthomatosis are also at an increased risk of developing cardiovascular disease or respiratory failure because of lipid accumulation in the heart or lungs, respectively. if untreated, the signs and symptoms related to cerebrotendinous xanthomatosis worsen over time; however, this condition varies greatly among those who are affected. medlineplus.gov