a drug used for sedation, anesthesia, and analgesia in large mammals.
street drugs such as heroin and cocaine are often “cut” with various adulterants (eg, amphetamines, clenbuterol, dextromethorphan, fentanyl, ketamine, levamisole, lidocaine, lysergic acid diethylamide [lsd], pseudoephedrine, quinine, scopolamine, xylazine). adulterants may be added to enhance mind-altering properties or to substitute for pure drug; their presence can make diagnostic and therapeutic decisions difficult. merckmanuals.com
infection was performed as described previously . briefly, humanized transgenic (htg) mice, sp-a1 (6a2, 6a4), sp-a2 (1a0, 1a3), sp-a1/sp-a2 (6a2/1a0, co-ex) and sp-a (ko) male and female mice (n = 4 for per group) were anesthetized with a mixture of ketamine and xylazine and infected with k. pneumoniae (~ 450 cfu/mouse) in 50 μl of pbs intratracheally for 18 h. nih.gov