any of several small belt-like regions.
we found that the expression of angptl2 was decreased by the methylation of its promoter region. multivariate logistic regression analyses revealed that the baseline level of serum angptl2 was an independent risk factor for the progression of dkd during follow-up periods. in cultured podocytes, angptl2 directly increased albumin permeability through the translocation of zonula occludens-1 from the membrane to the cytosol via activation of focal adhesion kinase. medpagetoday.com