zotarolimus Definitions


an immunosuppressant, a semisynthetic derivative of rapamycin.

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  • patients who were randomized to the polymer-free, sirolimus- and probucol-eluting isar des fared similarly over 10 years compared to peers who got durable-polymer, zotarolimus-eluting endeavor resolute des, reported sebastian kufner, md, of deutsches herzzentrum m√ľnchen, germany, and colleagues in the july 14 issue of the journal of the american college of cardiology. that was true for the following endpoints: medpagetoday.com

  • bare metal stents (bms) are made of nickel-titanium alloy. drug eluting stents (des) have drugs (eg, 1st-generation: sirolimus, paclitaxel; 2nd-generation: everolimus, zotarolimus) bonded to the metal that limit neointimal proliferation to reduce the risk of restenosis. radioactive stents or pre-stent intracoronary radiation using radioactive pellets (brachytherapy) have not proven effective at limiting restenosis. biodegradable stents are being developed, but use is currently limited to clinical trials. merckmanuals.com