an immunosuppressant, a semisynthetic derivative of rapamycin.
patients who were randomized to the polymer-free, sirolimus- and probucol-eluting isar des fared similarly over 10 years compared to peers who got durable-polymer, zotarolimus-eluting endeavor resolute des, reported sebastian kufner, md, of deutsches herzzentrum münchen, germany, and colleagues in the july 14 issue of the journal of the american college of cardiology. that was true for the following endpoints: medpagetoday.com
bare metal stents (bms) are made of nickel-titanium alloy. drug eluting stents (des) have drugs (eg, 1st-generation: sirolimus, paclitaxel; 2nd-generation: everolimus, zotarolimus) bonded to the metal that limit neointimal proliferation to reduce the risk of restenosis. radioactive stents or pre-stent intracoronary radiation using radioactive pellets (brachytherapy) have not proven effective at limiting restenosis. biodegradable stents are being developed, but use is currently limited to clinical trials. merckmanuals.com